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Raw Material Powder Coluracetam for Memory Enhance

in Antibiotic and Antimicrobial Agents, Type: sell

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  • Raw Material Powder Coluracetam for Memory Enhance
  • Saler at Wuhan Hezhong Biochemic...
    China
  • Our main products include steroid powder ,pharmaceutical raw materialand and peptides , which are widely used in health products for bodybuliding,muscle,weight loss and so forth.The Testosterone series,Tren A,Tren […]

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 Country Of Origin: China
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Description

Raw Material Powder Coluracetam for Memory Enhance

Name:Coluracetam
Molecular Formula:C19H23N3O3
CAS No.:135463-81-9
Purity:99%
Synonyms:N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide
Molecular Weight:341.40
Appearance:white crystal powder
Boiling Point:634.1°C at 760 mmHg °C
Application:mainly applied to promote intellectual product. /raw material used in Synthesis/ pharmaceutical raw material

Coluracetam (code name BCI-540; formerly MKC-231) is a nootropic agent of the racetam family.It was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depressive disorder (MDD), which was preceded by being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from phase IIa clinical trials have suggested that it would be a potential medication for comorbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.

Coluracetam enhances high-affinity choline uptake (HACU),which is the rate-limiting step of acetylcholine (ACh) synthesis. Studies have shown coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects in cholinergic neurotoxin-treated rats by changing the choline transporter regulation system.

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